| The Relationships between Exercise-mediated Fitness and Body Composition with Immune Response to Influenza Vaccine in Elderly Women |
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Ki-Jin Kim |
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Keimyung University |
Correspondence:
Ki-Jin Kim,
Email: kjk744@kmu.ac.kr
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Received: 5 November 2010 • Accepted: 11 December 2010 |
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| Abstract |
INTRODUCTION
The purpose of this study was to examine whether cardiovascular fitness was associated with immune responsiveness of T-lymphocyte to influenza vaccine after regular aerobic exercise in older women.
METHOD
Exercise group performed 12 week of recreational dance after influenza vaccine, but control group did not perform exercise program. Subjects were measured body composition, VO 2 max of graded treadmill testing, blood concentration of IgG1, IgG2, Il-10 and IFN-r concentration of ELISA at pre, mid and post-exercise. The relationship of change of cardiovascular fitness with immune responsiveness of T-lymphocyte to influenza vaccine after regular aerobic exercise program was analyzed by Pearson's corelation coefficients.
RESULT
Body composition, blood concentration of IFN-γ and IL-6 showed no significant difference after 12 week exercise program in both groups. Exercise group showed the increased tendency of blood concentration of IgG1 and IgG2 after exercise program. Exercise group showed a significant increase of VO 2 max after exercise program. This increase of VO 2 max showed a significant correlations with the activation of blood IgG1 concentration.
CONCLUSION
This study confirmed that the improvement of cardiovascular fitness was associated with cell-mediated immune responsiveness of T-lymphocyte to influenza vaccine after regular aerobic exercise in older women. |
| Keywords:
Immune function, Older women, Exercise, Cardiovascular fitness, Lymphocyte |
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