| The Association of Insulin Resistance, Adipocytokine, Cardiovascular Fitness and Heart Rate Recovery after Exercise in Adolescent |
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Seol-Jung Kang, So-Bong Jung |
Changwon National University
Kyeongsang National University |
Correspondence:
Seol-Jung Kang,
Email: sjkang803@hanmail.net
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Received: 30 January 2012 • Accepted: 21 April 2012 |
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| Abstract |
INTRODUCTION
The purpose of this study was to association of insulin resistance, adipocytokine, cardiovascular fitness and heart rate recovery after exercise in adolescent.
METHOD
The subjects were composed of obesity group(n=15), and normal group(n=15) in middle school. The body mass index(BMI), %fat, waist circumference(WC), insulin, systolic blood pressure(SBP), and diastolic blood pressure(DBP) were evaluated. The HOMA index were used as the insulin resistance, and insulin, fasting glucose, triglyceride(TG), HDL-C, adipocytokine(leptin, IL-6, TNF-α), C-reactive proteins(CRP) were measured. Exercise stress testing were performed according to the Bruce protocol. Heart Rate Recovery(HRR) were assessed by measuring the reduction of heart rate for 1 minutes after cessation of exercise.
RESULT
1. The insulin(p<.05), HOMA-IR(p<.05), WC(p<.001), free fatty acids(p<.05), TG(p<.01), SBP(p<.01), and DBP(p<.05) were significantly increased in obesity group compared to normal group, however fasting glucose, HDL-C was not significant different between groups. 2. The leptin(p<.01), and CRP(p<.05) were significantly increased in obesity group compared to normal group, however IL-6 and, TNFα was not significant different between groups. 3. The VO 2max were significantly decreased in obesity group compared to normal group(p<.01) and HRR were significantly delayer in obesity group compared to normal group(p<.001). 4. In correlation analysis showed that the insulin resistance were positively correlated with BMI(p<.001), %fat(p<.001), WC(p<.01), TG(p<.05), SBP(p<.05), DBP(p<.01), insulin(p<.001), leptin(p<.001), IL-6(p<.01), CRP(p<.01), and positively correlated with VO 2max (p<.05), HRR(p<.05). 5. In correlation analysis showed that the VO 2max were negatively correlated with BMI(p<.001), %fat(p<.01), WC(p<.01), SBP(p<.01), DBP(p<.001) fasting glucose(p<.05), leptin(p<.01), TNF-a(p<.05), resting heart rate(p<.05), and positively correlated with HRR(p<.05). 6. In correlation analysis showed that the HRR were negatively correlated with BMI(p<.001), %fat(p<.01), WC(p<.05), SBP(p<.05), DBP(p<.01), insulin(p<.05), and leptin(p<.05).
CONCLUSION
Insulin resistance was significantly associated with leptin, CRP, cardiovascular fitness and HRR in adolescent. |
| Keywords:
Adolescent, Insulin resistance, Adipocytokine, Cardiovascular fitness, Heart rate recovery |
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