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The Official Journal of the Korean Academy of Kinesiology 2011;13(3):53-62.
Published online July 30, 2011.
Effects of High Intensity Exercise on Inflammatory Responses in Athletes and Healthy Individuals
Hyun-Seung Rhyu, Hee-Tae Roh
Yonsei University
Correspondence:  Hee-Tae Roh,
Email: htroh@yonsei.ac.kr
Received: 30 April 2011   • Accepted: 16 July 2011

The purpose of the present study was to investigate the effect of acute high intensity exercise on inflammatory responses in athletes and healthy individuals.
In present study, treadmill running was carried out for 8 healthy individuals and 8 athletes at 85%V˙O 2max until the point of all-out. Blood samples were taken 3 times (Rest, immediately after exercise, and 4hour of recovery), and with the collected blood, reactive oxygen species (ROS), NKT cell, IFNγ, and TNF-α were analyzed.
V˙O 2max and exercise time to exhaustion were significantly higher for athlete group compared to healthy individual group (p<.05). ROS, NKT cell, IFN-γ, and TNF-α were significantly increased immediately after exercise (p<.05). ROS and IFN-γ were significantly higher for athlete group compared to healthy individual group (p<.05). NKT cell was significantly higher at immediately after exercise in individual group compared to in athlete group (p<.05).
These results suggest that how suitably an individual is now trained physically can play a positive role in reducing physical burden by increasing in-vivo adaptability, regulating the immune system, and also controlling inflammatory factors which can be involved in developing inflammatory disease.
Keywords: Severe exercise, Inflammation, ROS, NKT cell, Cytokine


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